NCT02916277Unknown不适用
Endocan; Can be a New Biomarker in Ventilator-associated Pneumonia?
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- relationship between the level of Endocan and development of VAP
研究概览
简要总结
In this study; in patients undergoing mechanical ventilation, making the day series Endocan measurements during the first 5 day to look at whether there is a relationship between the levels of VAP with Endocan. This relationship, if any, aimed to investigate whether correlated with clinical and laboratory findings [presence of fever, pathological lung X-ray, the number of white blood cells (WBC), procalcitonin (PCT), C-reactive protein (CRP)] .
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •over 18 age
- •Patients whether intubated and connected to a mechanical ventilator
排除标准
- •patients intubated due to lung problems such as COPD, asthma, pulmonary embolism , etc.
- •Patients with brain tumors
- •patients with acute and chronic renal failure
- •Patients with hypertension
- •Patients with previously diagnosed infection
- •Patients with extubated
- •patients using antibiotics or corticosteroids before bronchoalveolar lavage fluid samples taken
结局指标
主要结局
relationship between the level of Endocan and development of VAP
时间窗: 9 month
次要结局
- correlation with the level of Endocan and clinical and laboratory findings(9 month)
研究者
ILKE KUPELI
assist. prof.
Erzincan University
研究点 (1)
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