To Compare the analgesic efficacy of Ropivacaine versus Ropivacaine with Dexamethasone for Post-operative analgesia in Ultrasound guided TAP ( Transversus Abdominis Plane) block for Laproscopic Inguinal Hernia repair-a randomized doube blind controlled prospective study
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To evaluate the time of First rescue analgesia post-operatively
研究概览
简要总结
Laproscopic surgeries are commonly performed surgical procedures and these patients require a multi-modal post-operative pain treatment regimen. Regional anaesthesia techniques have shown to decrease consumption as well as its adverse effects.
Transversus Abdominis Plane (TAP) block is a regional anaesthesia technique that has been applied in multi-modal pain regimen in laproscopic and open abdominal surgeries for reduction in pain scores and opioid use,reduced incidence of post operative nausea and vomiting has also been noted.
Dexamethasone is a corticosteroid which has been used here owing to its anti-inflammatory properties and suppressing the synthesis and secretion of various inflammatory mediators has been found to prolong the period of analgesia upto 48 hrs.Use of Perineural Dexamethsaone has been associated with less analgesic consumption and a lower incidence of post-operative nausea and vomiting
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Double
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- Male
入选标准
- •ASA Grade 1 & 2 Patients in age group of 18-65 years posted for laproscopic inguinal hernia surgery Willing to participate.
排除标准
- •Patient refusal History of allergy or contraindication to study medicine ASA Grade 3 & 4 Drug or Alcohol abuse Surgery converted to open procedure.
结局指标
主要结局
To evaluate the time of First rescue analgesia post-operatively
时间窗: VAS scores will be assessed at 0hr,2hr,4hr,8hr,12hr,16hr,24hr | Total dose of rescue analgesia will be assessed in 24 hrs
Evaluate total doses of rescue analgesia in 24 hrs
时间窗: VAS scores will be assessed at 0hr,2hr,4hr,8hr,12hr,16hr,24hr | Total dose of rescue analgesia will be assessed in 24 hrs
次要结局
- Evaluate efficacy of TAP block in providing post-operative analgesia in laproscopic inguinal hernia surgeries(Evaluate safety and adverse effects of TAP block)
研究者
Dr Rajesh Kumar Harish
Fortis Hospital, Mohali