Predictive value of perianastomotic drain fluid biomarkers in anastomotic leak: a cohort study - NI

AIIMS NEW DELHI0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年6月24日

试验速览

暂无简介。

•1. 18 – 70 Years
•2. Both gender
•3. Post-operative abdominal surgery undergone intestinal anastomosis
•4. Patients can follow instructions and are ready for regular follow up
•5. Able to provide informed and written consent
•6. Non-trauma elective and emergency cases with small intestine perforation or obstruction.
•7. Mesenteric ischemia or strangulation: Small Intestinal obstruction with segmental ischemia or gangrene
•8. Tumour: small bowel mass , Small bowel malignancy with adequate negative margin
•9. Entero-cutaneous fistula
•10. Symptomatic benign disease such as Meckles diverticulum or perforated diverticulitis or intussusception of bowel needing resection and anastomosis
•11. Incarcerated hernia
•12. Patients with ileostomy for closure

•1. Age less than 18 years and more than 70 years
•2. Patients taking immunosuppressive therapy and chemotherapy.
•3. Patients with known hematological disorders or malignancy.
•4. Patients with known chronic liver or kidney disease
•5. Auto-immune disease or immunodeficiency syndrome
•6. Pregnant or lactating mother
•7. Refusal to consent or participate in the study
•8. Proximal diverting ostomy creation at the time of intestinal anastomosis
•9. Patients receiving Albumin Supplementation during the period of the study.
•10. Abdominal trauma with small intestine perforation or obstruction.
•11. Active inflammatory bowel disease (Crohn’s enteritis with complications)
•12. Anastomosis involving oesophagus, stomach, duodenum, colon and rectum
•13. Patients on immunosuppressive drugs, post-chemotherapy or post-radiotherapy

发起方

AIIMS NEW DELHI