MedPath

Evaluation of peri-implant crevicular fluid biomarkers and marginal bone loss in platform-switched and non-platform-switched implants: a randomised prospective clinical study

Not Applicable
Completed
Conditions
missing teeth
dental implants&#44
matrix metalloprotinases&#44
gingival crevicular fluids&#44
cytokines&#44
diagnostics
Registration Number
TCTR20200425004
Lead Sponsor
istanbul university scientific research project
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
27
Inclusion Criteria

an implant site without acute infection or bone defects; a bone crest ≥7 mm; a full-mouth plaque score (modified plaque index [mPI]) and full-mouth bleeding score (bleeding on probing [BOP]) ≤25%; ≤10 cigarettes per day if a smoker; and a peri-implant keratinised tissue width ≥2 mm.

Exclusion Criteria

systemic medical conditions such as diabetes and any medication that could influence healing of soft or hard tissue.
full-mouth plaque score (modified plaque index [mPI]) and full-mouth bleeding score (bleeding on probing [BOP]) more than 25%; 10 and more cigarettes per day if a smoker; and a peri-implant keratinised tissue width less than 2 mm.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
PICF LTB4 levels 1 year Elisa
Secondary Outcome Measures
NameTimeMethod
PICF MMP8/TIMP1 levels 1 year Elisa
© Copyright 2025. All Rights Reserved by MedPath