peri-implant crevicular fluid cytokine level using healing abutments

Phase 3

• Conditions: Peri-implant mucositis.; Presence of tooth-root and mandibular implants; Z96.5

• Registration Number: IRCT20160315027056N2
• Lead Sponsor: Vice Chancellor for Research and Technology, Kerman University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Age of the patient should be over 18
Implant treatment should be performed in patients with partial or complete edentulous
Bone level implant placement in one stage and obtaining suitable primary stability should be possible.
Good patient compliance, reference for follow-up visits and observation of post operation instructions should also be possible.

Exclusion Criteria

Patients who have periodontal disease
Conditions that affect the immune system such as diabetes and pregnancy
The habit of smoking and alcohol or tobacco consumption
History of Antibiotics, anti-inflammatory, and immunosuppressive drugs intake three months before the study.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Interleukin-1ß cytokine. Timepoint: Two months after the intervention. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) human kits (HANGZHOU EASTBIOPHARM CO.LTD.) for evaluation of interleukin 1ß levels.;Tumor Necrotizing Factor a cytokine. Timepoint: Two months after the intervention. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) human kits (HANGZHOU EASTBIOPHARM CO.LTD.) for evaluation of interleukin 1ß levels.

Secondary Outcome Measures

Name	Time	Method
Plaque Index (Ainamo & Bay 1975). Timepoint: 2 months after the intervention. Method of measurement: Observation in such a way that if the plaque is visible on each of the buccal, lingual, mesial or distal surface of healing abutment 0 code and if it is not visible code 1 is assigned.;Bleeding Index (Ainamo & Bay). Timepoint: 2 months after the intervention. Method of measurement: Observation in such a way that if bleeding on probing is visible on each of the buccal, lingual, mesial or distal surface of healing abutment 0 code and if it is not visible code 1 is assigned.