NL-OMON44354已完成不适用
Effect of total parenteral feeding on the postprandial bile acid response - TRENT
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Ability to provide informed consent
- •- 18 years or older at the time of signing the informed consent
- •- Body mass index (BMI) 18.5- 25 kg/m2
- •- Caucasian men
- •- General good health as determined by medical history, physical examination and blood chemistry by a physician.
- •-HOMA-IR index: * 2.0 (measured as fasting insulin (pmol/L) x fasting glucose (mmol/L) / 135)
排除标准
- •-Major illness in the past 3 months
- •-Use of any medication
- •-Gastro-intestinal disease that may influence bile acid metabolism
- •-History of cholecystectomy or other bile duct abnormalities
- •-Tobacco smoking
- •-Drugs abuse
- •-Alcoholism (>3 units a day)
- •-Allergy or intolerance to ingredients included in the standardized meals
- •-Blood chemistry:
- •*Creatinine >120 µM
- •*>2 times upper limit reference interval of the following: ASAT, ALAT, bilirubin, GGT and AF.
- •*Lipid spectrum
- •-Strenuous exercise for at least 3 days prior to each study day, defined as more than 1 hour of exercise per day.
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