NCT01700686已完成不适用
The Effect of Gastric Bypass Surgery on Gut Hormones Related to Bone Remodeling and Intestinal Growth.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Meal stimulated changes in gut hormones and bone markers.
研究概览
简要总结
The overall purpose is to explore the link between the gut and the bones by investigating meal stimulated changes in the blood level of a number of hormones and markers related to intestinal growth and bone turnover in patients undergoing surgery for obesity (gastric bypass). The hormones will be measured in blood samples taken before and after surgery. The results are compared with changes in body weight and body composition as measured by DEXA scanning.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Caucasians fulfilling the criteria for laparoscopic gastric bypass.
- •BMI>40kg/m2.
排除标准
- •Pregnancy
- •Chronic obstructive pulmonary disease
- •Diabetes mellitus
- •Chronic inflammatory bowel disease
- •Major psychiatric disorder
- •Drug abuse
结局指标
主要结局
Meal stimulated changes in gut hormones and bone markers.
时间窗: Before surgery and 4 weeks and 6 months after surgery.
次要结局
- Changes in bone mass and body composition.(Before surgery and 6 months after surgery.)
研究者
Bolette Hartmann
PhD
University of Copenhagen
研究点 (1)
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