Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone With the NOGA System
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Evolution of LLS (linear local shortening) via the NOGATM system in percentage
研究概览
简要总结
Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters.
However, no study has investigated whether these electrical changes are associated with mechanical changes in local contractility.
However, the voltage is closely correlated to the local contractile function as evidenced by the use of the NOGA system.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Patients who should undergo ventricular tachycardia (VT) ablation after a myocardial infarction according to current recommendations, namely: patients with ischemic heart disease (ICD) and with episodes of sustained ventricular tachycardia responsible for internal electric shocks by the implantable automatic defibrillator (ICD) (grade IB recommendation)
- •patients with an MIC and an ICD, presenting a first episode of sustained ventricular tachycardia (grade IIa, B recommendation)
- •Affiliated with a social protection scheme
- •Having signed an informed consent
排除标准
- •Contraindication or non-indication for ventricular tachycardia ablation
- •Women who are pregnant or of childbearing age and without contraception, breastfeeding women
- •Patients without ischemic heart disease
- •Patients under guardianship, curatorship or legal protection.
研究组 & 干预措施
NOGA TM probe
干预措施: NOGA TM probe (Device)
结局指标
主要结局
Evolution of LLS (linear local shortening) via the NOGATM system in percentage
时间窗: 1month
Study the change in percentage of LLS during stimulation in a post-infarction scar zone identified by voltage mapping of the left ventricle with the NOGA system, compared to LLS in the same zone measured in atrial stimulation
次要结局
- Evolution of global systolic function: left ventricular ejection fraction(1month)
- Evolution of the global systolic function: integral time velocity under aortic Translation results Evolution of the global systolic function: integral time velocity under aortic(1month)
- Evolution of the global systolic function: strain longitudinal global(1month)