Smell and taste with tube feeding to improve nutrition in very preterm infants: a randomized controlled trial.
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 396
研究概览
简要总结
This trial investigated the following question: if preterm born babies do regularly smell and taste their milk when they are fed through a tube in their stomach compared with routine care, do they grow better? Findings: A total of 396 preterm born babies receive one of either: regular exposure to the smell and taste of their milk with tube feeding compared with routine care. Smell and tast of their milk did not improve their weight at discharge. However, smell and taste of milk may improve head size and length at 36 weeks of gestational age but not at discharge. This means that although smell and taste of milk with tube feeding did not improve weight at discharge, the combination remains a simple and low-cost intervention without adverse effects and some potential benefits.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- Days 至 14 Days（—）
- 性别
- All
入选标准
- •< 29 weeks postmenstrual age and/or less than 1250 g birth weight
排除标准
- •1. infants with congenital conditions associated with the digestive system requiring surgery shortly after birth, e.g.: gastroschisis, any malformation requiring a stoma after birth (e.g.: anal atresia), oesophageal atresia.
- •2. Congenital conditions leading to impaired growth: e.g.: trisomy 21, trisomy 18, salt wasting enteropathy.