Nutrition and Medication Management in Home-dwelling Older Adults. Study II: Malnutrition in Older Adults: An Intervention Based on Medication Review and Individual Nutritional Plan
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Change from Baseline Body weight at 24th week
研究概览
简要总结
The project "Nutrition and Medication management in home-dwelling older adults" consist of two separate studies witch are described in the same study protocol. This is the second study in this Project. The first study (cross sectional) is described separately; Identification: 2017/12883-1
Undernutrition is common in older adults. The causes are many and include drug therapy. Drug side effects, as loss of appetite, nausea, or dry mouth, may contribute to malnutrition, impaired health and loss of function.
In patients with malnutrition or at risk for malnutrition we will evaluate an intervention consisting of:
- an "individual nutritional plan" with different measures aiming at improving nutritional status.
- a systematic drug review.
详细描述
The participants will be recruited by the home nursing services or by a nurse at a short-time ward in the nursing home.
The composite intervention consists has two components (A and B):
Component A: Clinical assessment and critical medication review
Drawing on information from the medical history, clinical finding according to examination made by the principal investigator (trained physician), information from the General Practitioner (GP) and the findings from blood tests, we will make a systematic and critical medication review. This systematic review has the following considerations:
- Are drug-drug unintended interactions likely to occur? Interaction analysis supported by https:// www.interaksjoner.no
- Are there use of potentially inappropriate medication? Assessed based on the Norwegian General Practice Nursing -Home criteria.
- Could nutritional related problems like loss of appetite, dry mouth and nausea, be attribute to adverse drug effects? Assessed by the list we made of drugs who often contributes to these side effects according to The Norwegian Pharmaceutical Product Compendium.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 70 year or more
- •Receiving home nurse care each second week or more often
- •Mini Nutritional Assessment short form (MNA-SF): 0-11 point (malnourished or at risk for malnutrition)
排除标准
- •Life expectance less than 6 month
- •Serious cognitive impairment
- •In need of enteral-/ parenteral nutrition
- •Not able to stand up for weight measure
- •The home care service are not responsible for medication delivery.
研究组 & 干预措施
Intervention group
Drug review and tailored nutritional supply.
干预措施: Individualized plan for improvement of nutrition (Dietary Supplement)
Intervention group
Drug review and tailored nutritional supply.
干预措施: Systematic drug review (Drug)
结局指标
主要结局
Change from Baseline Body weight at 24th week
时间窗: Baseline, 24th week
measurement of the participants weight
次要结局
- Change from Baseline Health- related quality of life at 24th week(Baseline, 24th week)
- Change from Baseline Activity of Daily living (ADL) at 24th week(Baseline, 24th week)
- Change from Baseline Admission to nursing home at 24th week(Baseline, 24th week)
- Change from Baseline Admission to hospital at 24th week(Baseline, 24th week)
- Change from Baseline Mini Nutritional Assessment short form (MNA-SF) at 24th week(Baseline, 24th week)
- Change from Baseline Number of drugs in daily use at 24th week(Baseline, 24th week)
- Change from Baseline Number of drugs in daily use considered inappropriate at 24th week(Baseline, 24th week)
- Change from Baseline Number of drugs in daily with high risk causing nausea, loss of appetite, and dry mouth at 24th week.(Baseline, 24th week)
研究者
Mari Fiske
Principal investigator
University of Oslo