跳至主要内容
临床试验/NCT05993208
NCT05993208已完成不适用

Correlation Between Optical Coherence Tomography and Multifocal Electroretinogram Findings With Visual Acuity After Vitrectomy Surgery for Retinal Detachment

New Valley University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
CMT,BCVAand mf-ERG were recoreded in 40 eyes of 40 patintes with vitrectomy for retinal detchament surgery .

研究概览

简要总结

Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity after vitrectomy surgery for Retinal detachment.

详细描述

Although the anatomical success rate of vitreoretinal surgery has improved over the last decade, visual results remain compromised? Patients with macula-off retinal detachments (RDs) can have poor visual recovery, specific color vision defects, or metamorphopsia postoperatively despite successful retinal reattachment. In these cases, subtle changes in the foveal structure may be causing visual disturbances that can be difficult to identify during standard clinical examinations such as slit lamp biomicroscopy or binocular indirect ophthalmoscopy .reported a possible association between incomplete visual recovery and the presence of residual subretinal fluid (SRF) postoperatively.

Optical coherence tomography (OCT) is a non-invasive technique that provides information about the morphology of the retina, and especially of the macular area in vivo. Some studies support the idea that OCT determines structural changes in the macula that are correlated with subjective visual function, including visual acuity (VA) in patients with vitrectomy for retinal detachment. Additionally, multifocal electroretinogram (m fERG) evaluation can be helpful in assessing macular function in post-vitrectomy. However, to date, there are relatively few reports concerning the combined use of OCT and m fERG for the correlation between retinal morphology and function of the macula in patients with vitrectomy for retinal detachment surgery. The purpose of our study is to determine whether a significant correlation exists between the amplitude of m fERG, visual acuity, and the morphological OCT changes by in the macula after vitrectomy for retinal detachment

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • patients with successful vitrectomy for retinal detachment.

排除标准

  • The patients who had vitrectomy for reasons other than retinal detachment surgery
  • Patients who had done scleral buckle surgery
  • Patients with media opacity are prevented from doing retina imaging.
  • Failed or recurrent vitrectomy surgery

结局指标

主要结局

CMT,BCVAand mf-ERG were recoreded in 40 eyes of 40 patintes with vitrectomy for retinal detchament surgery .

时间窗: 6 months

Each 10 um increase in central (CMT) associated by how increase decimal in Best corrected visual acuity and by how nV/deg2 increase multifocal electroretinogram in these eyes .

CMT(central macualr thikness ) um

时间窗: 6 month

centeral macualr thikness mesurment using using optical chorent tomgraphgy

mf-ERG amplituide nV/deg2

时间窗: 6 month

multifocal electroretinogram amplituide mesurement using mf-ERG machine

BCVA(best corrected visual acuity)

时间窗: 6 Month

Best corrected Visual acuity measurement using Snellen's Acuity Chart and will be expressed as decimal notation

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Asmaa Kamel Ahmed Hassan

lecture

New Valley University

研究点 (1)

Loading locations...

相似试验