EUCTR2010-020240-35-IT进行中（未招募）不适用
Significance of the FSH receptor polymorphism p.N680S for the efficacy of FSH therapy of idiopathic male infertility: a pharmacogenetic approach. - ND
AZIENDA OSPEDALIERA POLICLINICO DI MODENA0 个研究点目标入组 100 人开始时间: 2010年7月15日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- Male
入选标准
- •Male idiopathic infertility. Age 20-50. Sperm DFI >15%, homozygosity for FSHR genotype at position 680 (either N or S). Normal serum FSH (<8 UI/l)and reproductive hormone levels. Normal ovulatory cycles in the female partner.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •zoospermia, endocrine disorders, genetic disorders (chromosome abnormalities, congenital bilateral absence of the vas deferens, microdeletions within the AZF regions of the Y chromosome), varicocele, cryptorchidism, infections, immunological infertility, and obstructive infertility. In the female partner, known etiologies of infertility such as tubal blockage, endocrine abnormalities, anatomical abnormalities, endometriosis or infections are an exclusion criterion for the respective male partner.
研究者
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