DRKS00020212已完成不适用
Application of the urinary biomarkers TIMP2 and IGFBP7 as early predictors regarding procedure selection for negative fluid balance in septic patients - TIIGER study
niversitätsklinikum Knappschaftkrankenhaus BochumKlinik für Anästhesiologie, Intensivmedizin und Schmerztherapie0 个研究点目标入组 100 人开始时间: 2019年12月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Intensive care patients within 72 hours after diagnosis of sepsis (suspected infection / proof of infection and increase of the SOFA score by at least 2 points)
- •- Acute kidney damage according to KDIGO criteria with stage 2 or higher (increase of the creatinin value to at least 2 times the baseline or urine excretion <0.5 ml / kg / h over at least 12 hours)
- •- Medically indicated decision to perform a furosemide stress test for a negative fluid balance
排除标准
- •Age <18 years
- •- Pregnancy (positive test in women of childbearing age) or lactation
- •- Indication or decision for renal replacement therapy at the time of inclusion
- •- Pre-existing, higher grade chronic renal insufficiency (stage 4 or 5, i.e., GFR <30 ml / min)
- •- Performed renal replacement therapy in the last 90 days
- •- Missing urine excretion (anuria) at inclusion time to an extent making sufficient urine sampling impossible
- •- Kidney transplant within the last 12 months
- •- Intolerance or contraindication regarding administration of furosemide
- •- Expected life time <90 days due to medical conditions not related to sepsis or acute kidney injury
- •- Dependency relationship or employment relationship with the sponsor or examiner
- •- Persons acting on a court or administrative order in an institution are housed
- •- Other reasons which, according to the investigator, render the patient unsuitable for study enrollment
研究者
相似试验
招募中
不适用
Role of chemicals in urine for predicting renal failure in patients with muscle injuryCTRI/2018/05/013824AIIMS intramural fund
已完成
不适用
Predicting renal failure using urine test in patients admitted in the ICU after trauma.CTRI/2020/09/027662Department of Anaesthesiology and critical care JIPMER Puducherry79
招募中
不适用
The exploration of urinary biomarkers in patients with lower urinary tract dysfunctioower urinary tract dysfunctionJPRN-UMIN000029964Department of Urology, Hamamatsu University School of Medicine250
招募中
不适用
rinary Biomarkers: Analysis of Urine in patients with tubular and glomerular kidney diseaseN18N17Acute renal failureChronic kidney diseaseDRKS00010534Klinik II für Innere MedizinUniklinik Köln3,000
尚未招募
Unknown
Role of urine tests in knowing the type of kidney damage occurring in liver disease patientsCTRI/2023/11/059816Deep Patel