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临床试验/CTRI/2023/03/051196
CTRI/2023/03/051196尚未招募不适用

A comparative clinical study of intrathecal clonidine and dexmedetomidine added with bupivacaine for post-operative analgesia in gynaecological surgeries.

DR. YOGITA SORTE1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年1月4日最近更新:
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试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.
研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

VARIOUS CLINICAL STUDY HAVE FOUND THAT ADMINISTRATION OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE PROLONGS THE DURATION OF SENSORY AND MOTOR BLOCKADE AS WELL AS DURATION OF ANALGESIA. HOWEVER THESE ARE LIMITED DATA AVAILABLE ON COMPARING INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

研究设计

研究类型
Interventional
分配方式
Other
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)（—）
性别
Female

入选标准

  • •1.Informed written consent for participation in study.
  • •2.Patients posted for gynaecological surgeries.
  • •3.ASA physical status I and II.

排除标准

  • •Contraindication to subarachnoid block.
  • •Allergy to local anaesthetic or study drug.
  • •Uncontrolled or labile hypertension.
  • •Patients taking any analgesics, sedative or antihypertensive drugs.
  • •Neurological disorders.
  • •Psychiatric disorders.
  • •Uncooperative patients.

结局指标

主要结局

TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

时间窗: TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.

次要结局

  • TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.(TO STUDY AND COMPARE THE ONSET OF ANALGESIA, DURATION OF MOTOR BLOCKADE, DURATION OF SENSORY BLOCKADE, HAEMODYNAMIC PARAMETERS OF INTRATHECAL CLONIDINE AND DEXMEDETOMIDINE ADDED WITH BUPIVACAINE.)

研究者

发起方
DR. YOGITA SORTE
申办方类型
Other [self]

研究点 (1)

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