Prospective Evaluation of Next Generation CT Reconstruction
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 215
- 试验地点
- 1
- 主要终点
- Compare with respect to 6 image quality metrics the overall image quality from a research low radiation dose body CT utilizing advanced (model based) iterative reconstruction with a clinical standard radiation dose CT from the same subject.
研究概览
简要总结
Background:
- Computed Tomography (CT) is a scan that makes detailed pictures of the body. It uses radiation to do that. In 2011, about 85.3 million CT scans were done in the United States. But there is growing concern about the health effects of radiation. There are new and different ways to make CT pictures that use less radiation. Researchers want to learn whether these new methods create images that are similar to images from a traditional CT.
Objective:
- To learn if new CT imaging methods with less radiation make images that are similar to traditional ways.
Eligibility:
- Adults 18 years of age and older who are scheduled for a CT of the chest, abdomen and pelvis with contrast.
Design:
- Researchers will review participants medical records to see if they can be in this study.
- Participants may have blood drawn from an arm vein by a needle stick. The blood will be used to make sure they can be in this study and that it is safe for them to have contrast.
- During the participants CT scan appointment, one extra scan will be done using low radiation methods.
- During a CT scan, the participant lies on a table. A large x-ray machine takes pictures of the body.
详细描述
Computed Tomography uses ionizing radiation to make pictures of the body. Different methods of creating CT pictures have been developed that allow reductions in the amount of radiation. The purpose of this research study is to learn whether these new imaging methods using less radiation to create images are similar to the traditional and current method.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •INCLUSION CRITERIA:
- •Inclusion Criteria for Body CT:
- •Clinical indication for a chest, abdomen and pelvis CT with contrast
- •Age equal to or greater than 18 years
- •Able to understand and willing to sign the Informed Consent Form
- •Inclusion Criteria for Chest CT:
- •Clinical indication for a CT with or without contrast that includes the chest
- •Age equal to or greater than 18 years
- •Able to understand and willing to sign the Informed Consent Form
排除标准
- •Exclusion Criteria for Body CT:
- •Serum Cr > 1.5 mg/dL
- •Clinical CT scan with more than one contrast imaging phase (for example three phase liver)
- •Exclusion Criteria for Chest CT
- •1. Pregnancy
研究组 & 干预措施
Body CT group
100 subjects for a body CT
Chest Ct Group
115 subjects for a chest CT
结局指标
主要结局
Compare with respect to 6 image quality metrics the overall image quality from a research low radiation dose body CT utilizing advanced (model based) iterative reconstruction with a clinical standard radiation dose CT from the same subject.
时间窗: Baseline (Day 0)
次要结局
未报告次要终点