NCT00002276已完成不适用
Study of Bleeding Tendency, Platelet Function, and Pharmacokinetics of Azidothymidine (AZT) and Motrin (Ibuprofen) in HIV-Infected Hemophiliacs
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 试验地点
- 1
研究概览
简要总结
To determine if platelet dysfunction and/or pharmacologic drug interaction occurs in patients taking both AZT and ibuprofen, which might account for enhanced bleeding tendency.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 12 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must have:
- •Hemophilia.
- •HIV-seropositivity confirmed by Western Blot.
- •Prior Medication:
- •- AZT for study patients.
- •- Ibuprofen.
排除标准
- •Co-existing Condition:
- •Patients with the following symptoms and conditions are excluded:
- •Hospitalization for opportunistic infection, bacterial infection or malignancy.
- •Concurrent Medication:
- •AZT (for control group).
- •Antibiotics or other medication for opportunistic infection, bacterial infection, or malignancy.
- •Patients with the following prior conditions are excluded:
- •Hospitalization for opportunistic infection, bacterial infection, or malignancy.
- •Ibuprofen.
- •AZT 1-2 gm daily (for study patient) or not taking AZT (for control).
研究者
研究点 (1)
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