A comparative clinical study of effectiveness of Ayurvedic and Conventional management in the patients of Sandhigata Vata of Janu (Knee osteoarthritis) with special reference to quality of life
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Any change in western Ontario and McMaster University osteoarthritis (WOMAC) score from baseline to the end of 3rd, 6th and 9th weeks of follow ups
研究概览
简要总结
osteoarthritis one of the leading causes of disability worldwide.Undoubtedly modern medicine provides symptoms (painand swelling) related relief to the patient of osteoarthritis. However, doserelated toxicity & idiosyncrasy are the major obstacles for its long termmanagement. Effective management needs drug and measures tominimize pain along with repair and strengthen bone and cartilage. Ageold holistic Ayurvedic approach management not only break the pathogenesis ofdisease but also strengthen and enhance the body’s own healing process byimparting appropriate nutritional support and strengthening the immune system.In this concern by scanning large numbers of publication and reports TrayodashangGuggulu of Bhaishajya Ratnavali (26/98-101) as oral medication and Sahacharadi Taila of *Ashtanga Hridaya Chikitsa sthana (21/66-68)*as local medications will be selected as Ayurvedicmanagement in the cases of Sandhigatavataof Janu (osteoarthritis) andcategorized them as Ayurveda treated group. Besides, the study isalso comparing the effectiveness of an Ayurvedic intervention withparallel conventional standard intervention in patient with kneeosteoarthritis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Stratified block randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 50.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients fulfilling the Revised ACR 2016 criteria of Knee OA 2.Patients presenting with classical signs & symptoms of Osteoarthritis Knee 3.Patients’ age group between 50 years to 70 years irrespective of sex, religion, occupation and socioeconomic status.
- •4.Pain severity scale on VAS between 1 to 6 (i.e. mild to moderate) 5.Patients with BMD range of > -1.0 to -3.0 6.Patient with BMI >18.5 to<29.9 7.Patients who are willing to this trial.
排除标准
- •1.Patients not fulfilling the Revised ACR 2016 criteria of Knee OA 2.Patients not fulfilling the classical sign and symptoms of OA.
- •3.Patient’s age group < 50 and > 70 years.
- •4.Patients with BMD range of < -3.0 5.Patient with BMI <18.5 to >29.9 (WHO) 6.Pain severity scale on VAS<1 and >
- •7.Patients having systemic disorder (Diabetic mellitus, Hypertension and other illness ) which might interfere with the treatment.
- •8.Patient of Autoimmune disorders, metabolic joint disorders or other than OA.
- •9.Patients with infective Neoplastic and traumatic condition of Knee joint.
结局指标
主要结局
Any change in western Ontario and McMaster University osteoarthritis (WOMAC) score from baseline to the end of 3rd, 6th and 9th weeks of follow ups
时间窗: 63days
次要结局
- Assessment of changes in (clinical symptoms) subjective parameters and objective parameters from baseline to the end of 3rd, 6th and 9th weeks.(Assessment of quality of life by using World Health Organization Quality of life (WHOQOL) BREF questionnaire.)