The Effect of Exercise Training on Gait and Quality of Life in Patients With Early Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 35
- 试验地点
- 4
- 主要终点
- Change in Gait speed
研究概览
简要总结
The project aims to evaluate the effects of 24 weeks of treadmill training (TT), with and without a strengthening component, on functional mobility, gait and quality of life in patients with Parkinson's disease (PD). The rationale for a study of this type stems from the hypothesis that treadmill training may act as an external "pacemaker" and enhance some properties of gait. There is a need for larger scale randomized controlled trials comparing the effects of treadmill training to control groups that receive similar amounts of attention. To date, no study has combined TT and muscle strengthening, likely the optimal form of therapy. A kinesiologist supervises the training, 3 times per week, for a total of 72 one-hour exercise sessions. It is hypothesized that at the end of 6 months, treadmill training will considerably improve walking parameters and the well being of people with PD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of idiopathic Parkinson's disease
- •Stage of II or less on Hoehn and Yahr scale
排除标准
- •Having musculoskeletal impairments or having excessive pain in any joint that could limit participation in exercise program
- •Dementia (MMSE<24)
- •Having balance problems
- •Live beyond 45 minutes from Laval University
结局指标
主要结局
Change in Gait speed
时间窗: Baseline, 3 and 6 months
This measure was recorded using the GAITrite system
Change in Endurance walking
时间窗: Baseline, 3 and 6 months
This measure was recorded using the 6-minutes walk test
Change in Quality of life
时间窗: Baseline, 3 and 6 months
This measure was recorded using PDQ-39
次要结局
- Change in Postural Balance(Baseline, 3 and 6 months)
- Change in Spatiotemporal parameters of walking(Baseline, 3 and 6 months)
- Change in Cognitive impairment(Baseline, 3 and 6 months)
- Change in Fear of falling(Baseline, 3 and 6 months)
- Change in Depression and anxiety level(Baseline, 3 and 6 months)
- Change in Effects of symptoms and motor impairment(Baseline, 3 and 6 months)