跳至主要内容
临床试验/CTRI/2025/04/085901
CTRI/2025/04/085901尚未招募不适用

Volume study of superficial serratus plane block for breast surgeries: a prospective randomized study

Ruby hall clinic1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2025年10月5日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
36
试验地点
1
主要终点
Assessment of volume in analgesic efficacy of superficial serratus plane block in breast surgery

研究概览

简要总结

Serratus plane block (SPB) was introduced by Blanco et al  , is a novel form of

ultrasound-guided regional anaesthesia fascial plane block that can achieve

paraesthesia of the hemithorax. Surgery on the chest wall is relatively common

and can be associated with considerable postoperative discomfort and pain.

Breast cancer has continued to be the most common cancer afflicting women,

accounting for 31% of all new cancer cases in the female population . Every

year, thousands of patients undergo surgery in the region of the breast and

axilla. These procedures cause significant acute pain and may progress to

chronic pain states in 25–60% of cases . Blockade of the lateral cutaneous

branches of the thoracic intercostal nerves (T2–T12) will provide analgesia to

the anterolateral chest wall in this patient population  .

This fascial plane block has become popular in recent years because of its ease

of performance as compared with thoracic epidural or paravertebral block. Its

analgesic effectiveness has been reported for mastectomies, thoracotomies,

rib fractures, and chest drain insertions.

Previous cadaveric studies have examined the extent of dye spread and the

nerves involved.  However, the optimal plane and volume of injection for

maximal spread in the anterior chest wall and axilla have not been evaluated.

There has been limited study concerning the appropriate volume for this

block .

Hence our goal of this study is to evaluate the impact of volume, level, and site

of injection on the extent of injectate spread that can influence analgesic

coverage and role in chronic pain management.

研究设计

研究类型
Interventional
分配方式
Random Number Table
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
20.00 Year(s) 至 75.00 Year(s)(—)
性别
Female

入选标准

  • All adult female patients for elective surgery under general anaesthesia coming under physical status ASA1 and 2.

排除标准

  • No consent and cooperation for the procedure, Allergy to any drugs used in the study, Weight less than 50 kg or obesity bmimore than 35kg per m Liver disease, renal disease, arrhythmia Chronic pain Neuromuscular disease Pregnancy.

结局指标

主要结局

Assessment of volume in analgesic efficacy of superficial serratus plane block in breast surgery

时间窗: ANALGESIC EFFECT ACCESSED AT 0, 3, 6,12,18,24 HOURS.

次要结局

  • Adverse events & their role in chronic pain(AFTER 1 WEEK AND 3 MONTHS OF SURFERY)

研究者

申办方类型
Private hospital/clinic

研究点 (1)

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