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临床试验/NCT04157582
NCT04157582Unknown不适用

Effect of Pilates Training on Cognitive Functions in Patients With Stroke

October 6 University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2019年10月8日最近更新:
适应症

试验速览

阶段
不适用
入组人数
40
试验地点
1
主要终点
Measuring memory function

研究概览

简要总结

The purpose of the present study is to investigate the effect of pilates training on cognitive functions in patient with stroke

详细描述

Stroke remains a primary cause of morbidity throughout the world mainly because of its effect on cognition. Individuals can recover from physical disability resulting from stroke, but might be unable to return to their previous occupations or independent life because of cognitive impairments.

Post-stroke cognitive impairment is not a unitary syndrome but incorporates a variety of deficits in multiple domains such as attention, executive functions , memory, language and visuoperceptual abilities. Cognitive impairment occurs in up to 64% of people who have had a stroke and has been associated with a 3-fold increase in risk for mortality, institutionalization and decreased instrumental activities of daily living function.

Pilates training was developed by Joseph H. Pilates .It belong to a group of so-called Body-Mind Exercises, where the focus is on controlled movement, posture, and breathing .Pilates (pronounced: puh-lah-teez) improves mental and physical well-being , increases flexibility through controlled movements done as mat exercises.

Pilates training improve cognitive functions through increasing blood and oxygen flow to the brain , support neuronal survival in the developping brain ,Generate new neurons ,Provides mood enhancement ,Increases neurotransmitters and Neurotrophins assure the survival of neurons in areas responsible for learning, memory and higher thinking.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
50 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Forty patients with stroke (hemiparesis) with muscle power at least grade 3 according to manual muscle testing scale (Appendix VI) from both genders their ages will be ranged from 50-65years old.
  • Patients with ischaemic stroke in the domain of the carotid system.
  • All patients have mild cognitive deficits in domains ( memory, attention, orientation, perception and executive skills) with score <25 according to Montreal Cognitive Assessment (Appendix IV).
  • Duration of illness not less than six months and not more than 18 months.
  • Spastcity grade (1) according to the Modified aschworth scale (MAS) ( Bohannon and Smith, 1987)(Appendix III).
  • All patients in the study should be ambulant independently.
  • Medically and psychologically stable patients.
  • All patients will approve and sign a consent form (Appendix I).
  • All patients are litrate.

排除标准

  • Patients with hemiparesis with motor weakness or incoordination.
  • Patients with cardiovascular problems (uncontrolled hypertension ,unstable angina ,significant coronary heart disease and or congestive heart failure).
  • Patients with dementia with score <3 according to Mini cog test(Appendix V). .
  • Patients with Musculoskeletal problems (deformity or contracture).
  • Medically unstable and uncooperative patients.
  • Patients with Moderate and severe obesity (BMI≥ 35 kg/m2).
  • Patients with depression with score > 8 according to Hamilton depression rating scale (HAM-D) (Appendix VII).

结局指标

主要结局

Measuring memory function

时间窗: 45 days

Vienna test system

Measuring attention

时间窗: 45 days

Vienna test system

Measuring orientation

时间窗: 45 days

Vienna test system

Measuring perception

时间窗: 45 days

Vienna test system

Measuring executive skills

时间窗: 45 days

Vienna test system

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Raghda Nasr Ibrahim Nasr

Assistant Lecturer in Neurological Physical Therapy

October 6 University

研究点 (1)

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