NCT03173287Unknown不适用
Quantification of Hepatic Fibrosis by IVIM Sequences in 1.5T MRI.
University Hospital, Clermont-Ferrand2 个研究点 分布在 1 个国家目标入组 63 人开始时间: 2017年3月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 63
- 试验地点
- 2
- 主要终点
- Measured perfusion-related scattering value
研究概览
简要总结
Quantification of hepatic fibrosis by IVIM sequences in 1.5T MRI.
详细描述
Early and accurate diagnosis of hepatic fibrosis in patients with chronic liver disease is essential and essential. This assessment could be performed by a non-invasive MRI method.
The main objective of this study is to show that the measured perfusion-related scattering value (D *) is related to the hepatic fibrosis stage.
Secondary objectives
- Evaluation of infusion fraction (f) and fibrosis stage.
- Evaluation of molecular diffusion (D) and fibrosis stage.
- Evaluation of ADC and fibrosis stage.
- Assess whether there is a link between the etiology of fibrosis and the value of the diffusion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
盲法说明
Open
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing hepatic biopsy (trans-parietal or trans-jugular) in the context of liver disease
- •Signature of written consent
排除标准
- •Contra-indications to MRI
- •Refusal of protocol
- •Underage patients and protected adults
结局指标
主要结局
Measured perfusion-related scattering value
时间窗: at day 1
The main objective of this study is to show that the measured perfusion-related scattering value (D \*) is related to the hepatic fibrosis stage.
次要结局
- Measured perfusion-related of infusion fraction(at day 1)
- Measured perfusion-related of ADC(at day 1)
- Measured perfusion-related of molecular diffusion(at day 1)
研究者
研究点 (2)
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