The effect of prasugrel on endothelial function in ischemic heart disease patients - The effect of prasugrel on endothelial function in ischemic heart disease patients

department of cadiovascular medicine, Chiba university graduate school of medicine0 个研究点目标入组 30 人开始时间: 2016年4月1日最近更新: 2023年10月17日

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•The exclusion criteria included the following: patients with unstable hemodynamics; patients underwent PCI or CABG within 4 weeks; patients in whom prasugrel is contraindicated; patients with severe hepatic dysfunction(liver cirrhosis, fulminant hepatitis, AST >100IU/L, ALT >100IU/L or Total bilirubin >3.0mg/dL); patients with severe renal dysfunction(eGFR <30mL/min); patients <50kg; patients with thorombocytepenia(platelet cell <100000/microL); patients with pregnancy or suspected pregnancy; patients administrated with anticoagulants(warfarin, dabigatran, rivaroxaban, apixaban or edoxaban); patients undergoing thrombolytic therapy; patinets administrated ticlopidine, cilostazol or clopidogrel; patients added or changed the drug for hypertension, dyslipidemia, diabetes or hyperuricemia within 2 weeks before agreement with this study; patients judged not eligible in this study.

发起方

department of cadiovascular medicine, Chiba university graduate school of medicine