To Compare the Progressive Cracking Technique and Conventional Chop Technique on Corneal Endothelial Cells in Patients With Hard Nucleus Cataract
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- percentage of hexagonal cells of the cells marked
研究概览
简要总结
Approximately 60 participants at Eye Hospital of Wenzhou Medical University during January,2017 to June 2021 will be enroll in our study. And dived them randomly into 2 groups:Progressive Cracking Technique (30 eyes) and Conventional Chop Technique (30 eyes) .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cataract with Grade IV~V nucleus sclerosis
- •Cataract surgery is planned
- •The operation was successful without any complications
排除标准
- •Patients with other diseases that affect the corneal endothelium
- •Has a history of anterior segment surgery
- •Failure to cooperate with follow-up
结局指标
主要结局
percentage of hexagonal cells of the cells marked
时间窗: up to 1 months
represents the percentage of hexagon cells,the ideal value is above 50%
central corneal thickness
时间窗: up to 1 months
thickness in micrometer
corneal endothelial cell density
时间窗: up to 1 months
the number of corneal endothelial cells per unit area.
Coefficient of variation of endothelial cells
时间窗: up to 1 months
represents the variation coefficient of cell area
次要结局
未报告次要终点
研究者
Yune Zhao
Vice president of Eye Hospital of Wenzhou Medical University
Wenzhou Medical University