Rehydration With a Trace Mineral Supplement
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Net Fluid Balance
研究概览
简要总结
It is well established that post-exercise rehydration with electrolyte solutions is more effective than plain water. However, most commercially available drinks are high in electrolytes but lack some essential trace minerals. This study aims to examine the impact of a higher-electrolyte sports drink compared with a low-electrolyte, trace-mineral-rich solution and water on the time course and extent of rehydration after exercise-induced dehydration.
详细描述
Protocol Before the start of the study eligible participants will visit our lab to conduct a screening of medical history, weight, height, and a onetime assessment of body composition via BIA and Training history. This visit will take place at least one day before the actual start of the study and typically lasts no longer than 30 minutes. During this visit participants will be given two questionnaires, one regarding the physical activity readiness of the participant, and another one regarding their health history. If a participant does not meet the physical criteria and does not pass both questionnaires, they will be given a $25 digital Tango gift card for their brief visit to our lab. Participants who do pass will be given a scheduled date and time to visit the lab again for their first official trial.
At the start of the study subjects will visit the lab after at least 10h of fast and they will consume a light breakfast. An intravenous catheter will be place in an antecubital vein and a blood sample will be taken after 20 min for baseline. A baseline skin hydration reading will also be taken at this time. Subjects will void their bladders and a body weight will be taken.
Dehydration:
Consistent with the study by Shirreffs et al (2007) and based on our previous work, dehydration will be accomplished on the morning of testing via mild exercise and heat exposure to elicit a body weight loss of -2%. The subjects will perform four bouts of 25-minutes low-intensity exercise and 5 min rest (alternating cycling & walking) or till they reach -2% of body weight dehydration.
Rehydration:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Recreationally physically active: Training > 2x per week and ≤ 6hours per week
- •BMI of 18.5-29.9
- •Stable weight for the last 2 months (<5 pounds. fluctuation)
排除标准
- •Women who are pregnant, breast feeding, or planning to become pregnant during the trial
- •night shifting work
- •thyroid medication
- •bariatric surgery
- •cardiovascular disease
- •renal disease
- •hepatic disease
- •Participating in another study at the same time
- •Bodyweight <110 pounds
- •Currently Smoker
- •Major surgery, including abdominal, in the past 3 months or individuals who have planned surgery during the trial.
- •Alcohol or drug abuse within the last 12 months
- •High alcohol intake (average of > 2 standard drinks per day or > 10 standard drinks per week)
结局指标
主要结局
Net Fluid Balance
时间窗: at 60 minutes, 120 minutes, 180 minutes and 240 minutes of rehydration
Body water Retention after exercise-induced dehydration
Urine volume
时间窗: 1, 2, 3, and 4 hour of the rehydration period
Urine volume during the rehydration period
Skin Hydration
时间窗: 1, 2, 3, and 4 hours of the rehydration period
Skin hydration at the face assessed with a moisture meter.
Free water clearance
时间窗: 1, 2, 3, and 4 hours of the rehydration period
Free water clearance during the rehydration period
Osmotic Clearance
时间窗: 1, 2, 3, and 4 hours of the rehydration period
Osmotic renal clearance during the rehydration period
次要结局
- Stomach fullness(1, 2, 3, and 4 hours of the rehydration period)
- Gastrointestinal symptoms(At the end of the 4 hours rehydration period)
- Plasma Volume(1, 2, 3, and 4 hours of the rehydration period)
- Plasma Osmolality(1, 2, 3, and 4 hours of the rehydration period)
研究者
Stavros Kavouras
Professor and Assistant Dean
Arizona State University