Effectiveness of Exercise Applications on Hepatic Steatosis and Physical Fitness in Patients With Nonalcholic Fatty Liver Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 31
- 试验地点
- 2
- 主要终点
- FibroScan
研究概览
简要总结
Purpose of the study will investigate the effects of two different training programs on hepatic steatosis and physical fitness parameters. This trial is designed in a randomized controlled study plan and aerobic training (40 minutes) wil be combined with Whole Body Vibration Training (WBVT for 15 minutes) which is made up of a shorter time application. WBVT to be applied instead of the resistance exercises.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of NAFLD
- •Age range of 18-65 years
- •Participants who are not in an active exercise program
- •Participants who are not on an active diet program
排除标准
- •Pregnancy
- •Chronic inflammatory process
- •Rheumatic disease
- •Cognitive disorders
- •Obstacles to achieve physical performance tests
- •Presence of other conditions that may cause liver steatosis
- •Inability to do WBVT or Aerobic Exercises
研究组 & 干预措施
Experimental
干预措施: Aerobic Exercise (Other)
Control
干预措施: Aerobic Exercise (Other)
结局指标
主要结局
FibroScan
时间窗: 8 weeks
İn the Fibroscan measurement session, the patient lying supine, the tip of the transducer is placed on the skin between the ribs over the right lobe of the liver. At least 10 validated measurements with a ratio of interquartile range (IQR) and median LSM of less than or equal to 30 percent are required for an interpretation of significant fibrosis or cirrhosis.
次要结局
- Profile of liver enzymes(8 weeks)
研究者
Tülay Çevik
Principal Investigator
Okan University