Ultrasound-guided Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Post-operative Analgesia in Inguinal Hernia Repair Under General Anesthesia: a Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- The intensity of postoperative pain
研究概览
简要总结
Uncontrolled postoperative pain after inguinal hernia repair increases the incidence of postoperative complications.
详细描述
Inguinal hernia repair is one of the most common surgical procedures in the world. Annually, more than 20 million inguinal hernia repairs are conducted worldwide.
Uncontrolled postoperative pain increases the incidence of postoperative complications. Regional blocks, as a part of multimodal analgesia, can improve pain control in the postoperative period and reduce complications that may arise from using a single mode of analgesia. For example, reliance on opioid analgesia increases the incidence of pruritus, nausea, and vomiting, as well as respiratory depression.
Hebbard first described the ultrasound (US)-guided transversalis fascia plane (TFP) block in 2009. A local anesthetic (LA) injected between the transversus abdominis muscle and its deep investing fascia will block the anterior and the lateral branches of the T12 and L1 nerves.
Erector spinae plane block (ESPB) is a type of facial plane block in which local anesthetic is administered in the plane located between the erector spinae muscle and thoracic transverse process. ESPB blocks the transmission of nociceptive stimuli through the dorsal/ventral rami of the spinal nerve roots, prevents afferent stimuli transmission, and inhibits efferent activation of the sympathetic nervous system and can thus provide both somatic and visceral sensory blockade, which would make it an ideal regional anesthetic technique for abdominal surgery.The effect of ESPB is also achieved through the block of the lateral, posterior, and anterior thoracic wall resulting in multiple levels sensory blocks. Additional proposed mechanism of action could be explained by the epidural spread of the anesthetics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 65 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Male patients undergoing elective open unilateral inguinal hernia repair under general anesthesia, ASA status I-II, aged from 20 to 65 years old
排除标准
- •Contraindications to regional block (coagulopathy, infection at the needle insertion site, or diaphragmatic paralysis)
- •Altered cognitive function
- •Body mass index (BMI > 35 kg/m2)
- •Patients who have difficulty understanding the study protocol
- •Patients who have any known allergy to study medications
- •Advanced hepatic or renal failure
- •Chronic opioid consumption
- •Patient refusal
研究组 & 干预措施
Transversalis fascia plane (TFP) block
Patients will receive unilateral US-TFP block with bupivacaine 15 minutes before skin incision
干预措施: Transversalis fascia plane (TFP) block (Procedure)
Erector Spinae Plane (ESP) Block
Patients will receive unilateral US-ESP block with bupivacaine 15 minutes before skin incision
干预措施: Erector Spinae Plane (ESP) Block (Procedure)
结局指标
主要结局
The intensity of postoperative pain
时间窗: 24 hours after surgery
Assessed by the verbal analog pain scale graded from 0 to 10 (0 = no pain, and 10 = the worst possible pain)
次要结局
未报告次要终点
研究者
Seham Mohamed Moeen Ibrahim
Assistant professor of Anesthesia and Intensive Care
Assiut University
