Effect of Preoperative Gabapentine for Carpal Tunnel Syndrome
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 主要终点
- Pain Intensity
研究概览
简要总结
The purpose of this study was to evaluate the postoperative analgesic effect of preoperative gabapentine for carpal tunnel syndrome surgery.
详细描述
There was studied 40 patients. Group 1 patients received 600 mg of gabapentin 1 hour before surgery; G2 received placebo 1 hour before surgery.
Anesthesia was regional intravenous block. Postoperative analgesia when needed was with acetaminophen. If needed was administered codeine. The evaluation of neuropathic pain was made by DN4 questionnaire. Pain intensity was assessed by numeric scale at block and after 30min, 1h, 2h, 2wk, 4wk, 6m. It was noted the duration of analgesia, and the amount of acetaminophen and codeine.
The statistical program used for analysis of the results was the Instat Graph
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •carpal tunnel syndrome
排除标准
- •disorientation, psychiatric disease, myocardial ischemia, hypertension, arrhythmia, another pain syndrome, drug user, and pregnant
研究组 & 干预措施
sugar pill
Placebo group
干预措施: Sugar pill (Other)
preoperative gabapentine,
Gabapentine
干预措施: Gabapentine (Drug)
结局指标
主要结局
Pain Intensity
时间窗: 6 months
Numerical score from 0 to 10; zero means no pain and 10 is the more intense pain
次要结局
- Chronic Pain(6 months)
研究者
Rioko Kimiko Sakata
Pain Clinic Director
Federal University of São Paulo