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临床试验/NCT07486661
NCT07486661招募中不适用

A Pilot Project for PLWH Aged 65-75: Preventing the Development of Frailty

Centre Hospitalier Universitaire Saint Pierre1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年8月28日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
100
试验地点
1
主要终点
number of PLWH between 65 and 74 years with frailty

研究概览

简要总结

In ageing populations, the main risk is the development of a syndrome of frailty, characterized by the addition of polymorbidity, polymedication, psychosocial difficulties, cognitive disorders, ... This functional decline is linked to a reduction in the person's functional reserves, and will lead to an increase in health problems, hospitalizations and, ultimately, mortality. People living with HIV (PLWH) over 50 develop the same kind of comorbidities as HIV-uninfected people over 75 years-old.

In Belgium, the care of PLWH< 75 years with frailty syndrome is not reimbursed by healthcare insurance, and geriatric assessment and management is therefore not possible in this age group, despite the very real need.

Goals of this project are:

  1. Determine the proportion and characterize the population of PLWH aged 65 and over who screen positive using the Fried scale
  2. Validate the application of the Fried scale in a population of PLWH
  3. Offer a care pathway model to prevent the onset of frailty in people screened as at-risk and who do not benefit from routine screening or care pathway reimbursement.

Projets proposal:

  • Systematic screening of all PLWH aged 65-74 at the MIA Center, by the nurse prior to physician consultation, using the Fried scale.
  • Send all PLWH aged 65-74 who screen positive to Geriatric One Day for an ergo-geriatric consultation to confirm the risk of frailty and set up a preventive care pathway
  • After treatment, perform a patient satisfaction questionnaire + a new Fried scale at one year

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 74 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • living with HIV
  • between 65-74 years

排除标准

  • 未提供

结局指标

主要结局

number of PLWH between 65 and 74 years with frailty

时间窗: Baseline

Using Fried scale and complete geriatic assesment The Fried scale is a widely recognized assessment tool designed to evaluate frailty in older adults, particularly those aged 65 and above. It helps identify individuals at increased risk of adverse health outcomes, such as falls, hospitalization, disability, and mortality. The assessment is based on five key criteria: unintentional weight loss, exhaustion, low physical activity, slowness, and weakness, with each positive criterion scoring one point. Scores of 0 indicate a robust individual, 1-2 suggest a state of pre-frailty, and ≥3 confirm frailty.

次要结局

  • Number of PLWH with a Fried test detecting frailty(Baseline)
  • Number of PLWH with Fried scale detecting pre-frailty condition(Baseline)
  • Results of Fried scale at one year(one year after the first Fried scale performed at baseline)

研究者

发起方
Centre Hospitalier Universitaire Saint Pierre
申办方类型
Other
责任方
Sponsor

研究点 (1)

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