Omega-3 polyunsaturated fatty acids and psychological interventions for workers with mild to moderate depression: a randomized controlled trial - Healing worker's depression by omega-3 polyunsaturated fatty acids and psychological interventions: a randomized controlled trial

After 12 weeks of treatment, BDI-II scores were significantly lower in the placebo and omega-3 group, when compared to their respective baseline scores (Placebo: t=-4.6, p<0.01; Omega-3: t=-7.3, p<0.01). However, after 12 weeks of treatment, we found no significant difference between both groups with respect to changes in the BDI-II scores (0.7; 95% CI, -0.7 to 2.1; p=0.30).