NCT05603221招募中不适用
Perfusion Assessment Using Arterial Spin Labelling MRI and Flat-panel Detector Parenchymal Blood Volume Imaging in Endovascular Treatment of Renal Artery Stenosis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Perfusion of the target kidney assessed by Arterial Spin Labelling MRI
研究概览
简要总结
The clinical benefits of endovascular treatment in renal artery stenosis remain controversial. This study uses arterial spin labelling MRI and flat-panel detector parenchymal blood volume imaging to observe the change in renal perfusion after endovascular treatment in renal artery stenosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who provided informed consent
- •patients who were diagnosed with RAS by CTA, MRA, or Doppler ultrasonography
- •patients who were aged 18 years or older
- •patients whose intervened renal arteries were not completely occluded (confirmed by DSA)
- •the stenosis percentage exceeding 70%
- •patients who had uncontrolled blood pressure or impaired renal function
- •paitents whose affected kidney did not have total loss of function
排除标准
- •were pregnant
- •had a history of renal transplantation or renal artery bypass surgery
- •were allergic to iodine contrast medium
- •had other contraindications of endovascular treatment
- •contraindications of MRI examinations
- •had technical failure in the endovascular treatment.
结局指标
主要结局
Perfusion of the target kidney assessed by Arterial Spin Labelling MRI
时间窗: Changes from baseline renal perfusion at 2 months
Perfusion of the target kidney assessed by Flat-panel Detector Parenchymal Blood Volume Imaging
时间窗: Changes from baseline renal perfusion immediately after endovascular intervention
次要结局
- Blood pressure(Changes from baseline blood pressure at 1 year)
- Renal function(Changes from baseline renal function at 1 year)
研究者
研究点 (1)
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