Development of a nociceptive test battery - acute pain tests - Development of pain tests battery

Centre for Human Drug Research0 个研究点目标入组 20 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

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•* Agree to and be capable of signing an informed consent form.
•* Healthy male and female subjects;
•* Age: 18 to 65 years at screening (inclusive);
•* Body mass index between 18-30 kg*m-2 (inclusive);
•* Able to refrain from strenuous physical exercise from 48 hours prior to each nociceptive test until dismissal from the CHDR clinic;
•* Able to refrain from alcohol use from 24 hours prior to and for the duration of every stay at the CHDR clinic;
•* Ability to communicate well with the investigator in the Dutch language.
•* Ability for female subjects to attend study days while in the follicular phase (3-13 days after onset of menstruation).

•* Legal incapacity or inability to understand or comply with the requirements of the study;
•* Any current, clinically significant, known medical condition in particular any existing conditions that would affect sensitivity to cold (such as atherosclerosis, Raynaud*s disease, urticaria, hypothyroidism) or pain (paraesthesia, etc.);
•* Pregnancy
•* History or clinical evidence of alcoholism or drug abuse;
•* Use of prescription, illicit or herbal medication within 7 days of nociceptive assessments;
•* Use of over-the-counter medications within 3 days of nociceptive assessments.

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