Einfluss Von Laufbändern für Büroarbeitsplätze Auf Ergonomie, Heizenergiebedarf, Leistungsfähigkeit Sowie Rücken- Und Kardiometabolische Gesundheit
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- Subjective thermal comfort rating
研究概览
简要总结
The aim of the project is to gain insights into the effects of treadmills at a standing desk and reduced room temperature on back and cardiometabolic health, cognitive performance, thermal comfort, and the associated heating energy requirements of buildings.
Healthy young men and women will spend four consecutive days in a controlled laboratory office environment after a baseline visit. During the baseline visit, volunteers are familiarized with the treadmill and start wearing a continuous glucose monitor. The four consecutive laboratory office days are each scheduled from 8:30AM to 04:30PM. In a randomized order, participants the first two office days either at 19°C or 23°C room temperature. The first office day of each temperature conditions is spent only sedentary, while for the second one is regularly interrupted with light walking on the treadmill. Otherwise, the daily routine and test battery will be exactly the same between days, including a standardized breakfast and lunch meal, an attention task in the morning, and frequent subjective thermal comfort ratings and blood pressure measurements. Interstitial glucose as well as heart rate and heart rate variability will be continuously monitored through wearable devices. Treadmill walking will be videorecorded.
详细描述
This is a controlled intervention study with a crossover design. Participants are assigned to different conditions in which they perform both sedentary and walking desk activities at different room temperatures.
Intervention conditions:
I: Sedentary activity at standard room temperature (23°C) II: Walking activity at standard room temperature (23°C) III: Sedentary activity at lowered room temperature (19°C) IV: Walking activity at lowered room temperature (19°C)
Each condition is carried out over a defined period, with corresponding 24-hour washout periods between conditions to minimize carry-over effects.
Participants are expected to attend a total of five in-person appointments at the indoor climate laboratory of the Chair of Building Services Engineering at RWTH Aachen University. On Day 0, an introduction to the local conditions will take place before the actual study week begins, and the continuous glucose monitor is individually placed on the upper arm. In the following study week, four consecutive experimental study days are planned. Participants will go through two different scenarios: Six participants will first experience a warm exposure for two days, followed by a cold exposure for two days, while the other six will start with a cold exposure and end with the warm exposure. Allocation of participants to the two sequences of the four experimental conditions (Sequence 1: I-II-III-IV; Sequence 2: III-IV-I-II) is performed using stratified block randomization. A computer-generated randomization procedure is used to ensure that participants are evenly distributed between both sequences. Randomization is carried out before the first test session. To ensure a balanced gender distribution, ideally three men and three women will start with Sequence 1, and three men and three women with Sequence 2.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Physically active, healthy test subjects
- •Participants who are able to understand the research project
- •Adult test volunteers (aged >18 and <40)
- •German language skills at B2-C2 level
排除标准
- •An implanted pacemaker
- •Participants who are unable to give consent/participants with a legal representative
- •Age under 18 or over 40
- •Pregnant participants
- •Participants with a BMI >28
- •Participants with underlying diseases with significant functional limitations (e.g., rheumatoid arthritis, diabetes mellitus, high blood pressure)
- •Reading and/or spelling disorders or combined disorders of scholastic skills (ICD-10 F81.0 - F81.3)
- •Participants with a possible SARS-CoV-2 infection will be excluded from the study for the duration of the infection
结局指标
主要结局
Subjective thermal comfort rating
时间窗: At regular intervals over each of the four laboratory office days
Interstitial glucose levels
时间窗: Continuously sampled every 15 min over all four laboratory office days
Interstitial glucose levels measured by continuous glucose monitors
Working memory assessed by the TAP (Zimmermann & Fimm, 2002) n-back task
时间窗: 10:00-11:00 AM during each of the four laboratory office days
Participants view sequences of numbers and indicate whether the current number matches one presented one or two steps earlier. Outcome variables are accuracy (% correct) and reaction time (ms).
Divided attention assessed by the TAP (Zimmermann & Fimm, 2002) divided attention task
时间窗: 10:00-11:00 AM during each of the four laboratory office days
Participants simultaneously perform a visual and an auditory discrimination task. Outcome variables are reaction time (ms) and error rates.
次要结局
- Heart rate(continuously from 08:30AM to 04:30PM over all four laboratory office days)
- Heart rate variability(continuously from 08:30AM to 04:30PM over all four laboratory office days)
- Systolic and diastolic blood pressure(at 09:00, 11:00, 12:30, 14:30 and 16:00 over all four laboratory office days)
- Skin temperature(continuously from 08:30AM to 04:30PM over all four laboratory office days)
- Intrinsic and phasic alertness assessed by the TAP (Zimmermann & Fimm, 2002) alertness task(10:00-11:00 AM during each of the four laboratory office days)
- Cognitive flexibility assessed by the TAP (Zimmermann & Fimm, 2002) task-switching module(10:00-11:00 AM during each of the four laboratory office days)
- Sustained attention assessed by the TAP (Zimmermann & Fimm, 2002) sustained attention task(10:00-11:00 AM during each of the four laboratory office days)
- Hip joint angles and dynamics during gait assessed by sagittal plane video analysis(During the walking period between 10:00-11:00 AM on each of the 4 laboratory days)
- Knee joint angles and dynamics during gait assessed by sagittal plane video analysis(During the walking period between 10:00-11:00 AM on each of the 4 laboratory days)
- Spinal joint angles and dynamics during gait assessed by sagittal plane video analysis(During the walking period between 10:00-11:00 AM on each of the 4 laboratory days)
研究者
Jan-Frieder Harmsen
Principal Investigator
RWTH Aachen University