A COMPARATIVE EVALUATION OF EFFICACY OF LOW LEVEL LASER THERAPY IN ACCELERATION OF ALIGNMENT OF CROWDED MANDIBULAR ANTERIORS – A RANDOMISED CONTROLLED CLINICAL TRIAL
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Increase in rate of orthodontic tooth movement and accelerated alignment of crowded mandibular anteriors
研究概览
简要总结
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• Low Level Laser Therapy have photobiomodulation effect on bone as it activates cytochrome-c oxidase and increases mitochondrial ATP and RANKL which accelerates cellular turnover (i.e. osteoblast, osteoclast, fibroblast). Hence bone remodeling occur.
• Previousstudies evaluated the acceleration rate of orthodontic tooth movement in crowded maxillary incisors, in space closure & pain reduction. None of the study was conducted on alignment of crowded mandibular anteriors.
The present clinical study aims to access acceleration of orthodontic tooth movement using Low Energy Laser Therapy during leveling and alignment phase in crowded mandibular anteriors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 16.00 Year(s) 至 25.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Systemically healthy patients in the age range of 16-25 years.
- •2.Moderate Crowding according to Little’s irregularity index (>5-9mm).
- •3.Therapeutic extraction cases of Lower first premolars.
- •4.Completely Erupted Permanent Mandibular teeth 5.Angle’s Class I & Class II malocclusion.
排除标准
- •1.Severely displaced teeth 2.Patients on medication such as NSIADS and Hormone supplements.
- •3.Spacing 4.Periodontally compromised patients 5.Systemic Diseases 6.Patient requiring extraction of lower incisor for crowding correction.
结局指标
主要结局
Increase in rate of orthodontic tooth movement and accelerated alignment of crowded mandibular anteriors
时间窗: 0,4,8,12,16 weeks
次要结局
- Reduction of pain during alignment(Every 4 weeks pain assessment will be done)