NCT03584841Unknown不适用
Implementation of a Non-invasive Version of the Imaging β-adrenergic-dependent Sweat Secretion Test: Value for Diagnosis and Efficacy of Target Therapies for Cystic Fibrosis
Cliniques universitaires Saint-Luc- Université Catholique de Louvain2 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2017年3月31日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- Ratio between the β-adrenergic/cholinergic rate
研究概览
简要总结
The goal of this study is to implement a non-invasive version of the sweat secretion test based in visualization of sweat glands following β-adrenergic stimulation of sweat. Specifically, the trial will evaluate the relative response of sweat glands to β-adrenergic and cholinergic stimulation among participants with CF, heterozygous and matched control subjects
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For patients with cystic fibrosis: clinically stable, all genotypes included.
- •For healthy volunteer and heterozygous subjects: 18 years and older.
排除标准
- •Corticosteroids, anti-leukotriene therapy, unstable clinical status, <40% FEV
- •Current pregnancy or breastfeeding.
结局指标
主要结局
Ratio between the β-adrenergic/cholinergic rate
时间窗: up to 30 minutes
The ratio between the β-adrenergic/cholinergic rate (nL/min) of droplets of sweat is calculated.
次要结局
未报告次要终点
研究者
研究点 (2)
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