PROUD Study - Preventing Opioid Use Disorders
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 57
- 试验地点
- 1
- 主要终点
- Total Post-operative Opioid Requirements With Non-opioid Drug Regimen
研究概览
简要总结
The objective of this study is to pilot an opioid free anesthetic protocol for patients undergoing total hip replacement.
详细描述
The objective of this study is to pilot an opioid free anesthetic protocol for patients undergoing total hip replacement. The study team identified alternative pharmacologic methods to block pain pathways to reduce or even eliminate the need for opioids in the intra- and postoperative periods, with the goal of decreasing or eliminating exposure to opioids. A secondary objective is to assess two core competencies for interprofessional collaborative practice (Interprofessional Communication and Teams; and Teamwork) within the interprofessional care team implementing the opioid free protocol.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Participants that do not speak English will not be eligible for participation in the study.
- •Individuals less than 18 years of age will not be included for participation in the study.
- •Individuals with cognitive impairment or the inability to provide informed consent will not be included in the study.
研究组 & 干预措施
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Guided mindfulness exercises (Behavioral)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Self-administered aromatherapy (Other)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Baby aspirin (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Tylenol/Acetaminophen (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Pregabalin (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Prednisone (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Meloxicam (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Prilosec (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Tramadol (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Voltaren (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Zofran (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Pepcid (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Reglan (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Versed (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Lidocaine (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Propofol (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Ancef (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Tranexamic Acid (TXA) (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Decadron (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Bupivacaine hydrochloride (Drug)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
干预措施: Toradol (Drug)
结局指标
主要结局
Total Post-operative Opioid Requirements With Non-opioid Drug Regimen
时间窗: Up to 5 weeks
Total post-operative opioid requirements (opioid dose) were calculated for participants receiving the non-opioid drug regimen, among participants who required post-operative opioid medication.
次要结局
- Nebraska Interprofessional Education Attitude Scale (NIPEAS) Score for Professional Staff Arm(Prior to protocol implementation (baseline), halfway through the recruitment period (2 months) and after the last participant has been discharged from the hospital (4 months))
研究者
Kelly Wiltse Nicely
Assistant Professor
Emory University