Evaluation of Human Efficacy of SOD Like Super Drink
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- the change of Glutathione (GSH) of blood
研究概览
简要总结
To assess the efficacy of SOD like Super Drink on anti-oxidant capacity, immuno regulation and skin for human
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 30 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy adults aged between 30-65 years old
排除标准
- •Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder
- •Patients with diseases of the skin, liver, kidney.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •Received facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 4 weeks.
- •Students who are currently taking courses taught by the principal investigator of this trial.
研究组 & 干预措施
placebo drink
干预措施: placebo drink (Dietary Supplement)
SOD like Super Drink
干预措施: SOD like Super Drink (Dietary Supplement)
结局指标
主要结局
the change of Glutathione (GSH) of blood
时间窗: Change from Baseline GSH at 8 weeks
venous blood was sampled to measure GSH
the change of Superoxide Dismutase (SOD) of blood
时间窗: Change from Baseline SOD at 8 weeks
venous blood was sampled to measure SOD
the roughness of skin texture
时间窗: Rating skin roughness from Baseline skin texture at 8 weeks
IRV full-face skin analyzer was utilized to measure skin texture. Units: arbitrary units
the change of skin elasticity
时间窗: Change from Baseline skin elasticity at 8 weeks
Cutometer® was utilized to measure skin elasticity. Units: arbitrary units
the change of Total Anti-oxidative Capacity (TAC) of blood
时间窗: Change from Baseline TAC at 8 weeks
venous blood was sampled to measure TAC
the change of Glutathione S-transferase (GST) of blood
时间窗: Change from Baseline GST at 8 weeks
venous blood was sampled to measure GST
the volume of skin wrinkles
时间窗: Volume change from Baseline skin wrinkles at 8 weeks
IRV full-face skin analyzer was utilized to measure skin wrinkles. Units: arbitrary units
the change of Malondialdehyde (MDA) of blood
时间窗: Change from Baseline MDA at 8 weeks
venous blood was sampled to measure MDA
the change of immune-related cytokines of blood
时间窗: Change from Baseline immune-related cytokines at 8 weeks
venous blood was sampled to measure immune-related cytokines
次要结局
- the change of skin Transepidermal Water Loss (TEWL)(Change from Baseline TEWL at 8 week)
- the change of skin surface hydration(Change from Baseline skin surface hydration at 8 week)
- the change of Skin Erythema Index(Change from Baseline skin Erythema Index at 8 week)
- the change of Skin Melanin Index(Change from Baseline skin Melanin Index at 8 week)