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临床试验/NL-OMON47690
NL-OMON47690已完成不适用

on-invasive assessment of lung remodelling in patients with pulmonary arterial hypertension (PAH) using [18F]-FLT PET imaging. - Imaging the primary disease process in PAH

Vrije Universiteit0 个研究点目标入组 36 人开始时间: 待定最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
36

研究概览

简要总结

Trial ended prematurely

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 64(—)

入选标准

  • In order to be eligible to participate in this study, a subject must meet all of the following criteria:
  • 1.Diagnosis of PAH, according to ESC/ERS guidelines (ref: Galie ERJ 2015)
  • Unaffected BMPR2 mutation carrier
  • Normal control subjects
  • 2. Age >50 and <80 years

排除标准

  • - Pregnant subjects
  • - Claustrophobia
  • - Inability to provide informed consent
  • - In case of PAH patients: TLC < 70%pred or radiographic evidence of interstitial lung disease
  • - In case of BMPR2 mutation carriers and normal control subjects, one or more of the following: abnormal spirometry, TLC < 70%, echocardiographic evidence of pulmonary hypertension

研究者

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