NCT04012658招募中不适用
A Registered Cohort Study on Wilson's Disease
Wan-Jin Chen1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2019年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- The change of Unified Wilson's Disease Rating Scale (UWDRS)
研究概览
简要总结
The aim of this study is to determine the clinical spectrum and natural progression of Wilson's Disease in a prospective multicenter natural history study, to assess the clinical, genetic, epigenetic features and biomarkers of patients with Wilson's Disease to optimize clinical management.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with the genetic diagnosis of Wilson's Disease
- •Asymptomatic Wilson's Disease carriers
- •Relatives of Wilson's Disease patients or carriers
- •Unrelated healthy controls
- •Participants or Parent(s)/legal guardian(s) willing and able to complete the informed consent process
排除标准
- •* Participants are unable to comply with study procedures and visit schedule
结局指标
主要结局
The change of Unified Wilson's Disease Rating Scale (UWDRS)
时间窗: Up to 30years
Disease severity will be assessed by application of the Unified Wilson's Disease Rating Scale (UWDRS), a clinical rating scale consists of three subscales. Higher UWDRS total scores indicate more severe disease.
次要结局
未报告次要终点
研究者
Wan-Jin Chen
The Vice-Director for the Department of Neurology
First Affiliated Hospital of Fujian Medical University
研究点 (1)
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