Collection of Tumor Tissue, Blood and Spinal Fluid From Patients With Brain or Spine Tumors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,128
- 试验地点
- 1
- 主要终点
- To establish a repository of CNS tumors or metastases to the CNS and related tissues for current or future studies.
研究概览
简要总结
The purpose of the study is to collect samples of brain or spine tumors. Memorial Sloan-Kettering Cancer Center would then store them for use by researchers who study brain or spine cancer and try to find better ways of treating it. We will also collect blood and spinal fluid from patients with brain or spine tumors. The blood and spinal fluids are also used for research studies of cancer and its treatment.
详细描述
The main objective of the protocol is the establishment of a repository of central nervous system (CNS) tumors or metastases to the CNS and related tissues as an invaluable resource for current or future research studies of the etiology, pathogenesis and treatment of human central nervous system tumors. The database will be established through the intra-operative acquisition of brain or spine tumors as well as the collection of blood and spinal fluids from consenting CNS tumor patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •For acquisition of intra-operative brain or spine tumor specimens, blood specimens and spinal fluid specimens, all patients who undergo surgery for resection or biopsy qualify for inclusion in this protocol.
- •If spinal fluid is not accessed as part of the operative procedure, it will not be collected.
- •All patients must be under the care of one or more members of the MSKCC CNS disease management team at the time of tissue acquisition. Patients may have been previously diagnosed and/or treated at another institution.
- •Subjects are eligible regardless of sex, age or race.
- •Parental or guardian consents will be obtained in the case of minors (less than 18 years of age)
排除标准
- •Patients or their guardians, in case of a minor, may choose to be excluded at any time.
- •If a patient, or guardian, decides to withdraw after some or all of the tissues have been collected, such tissues will be destroyed at their request.
- •Patients or their guardians will be counseled at the time of obtaining their consent, of the possibility of withdrawing from the protocol.
结局指标
主要结局
To establish a repository of CNS tumors or metastases to the CNS and related tissues for current or future studies.
时间窗: conclusion of the study
次要结局
未报告次要终点