Effects of Tai Chi on Multisite Pain and Brain Functions in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 54
- 试验地点
- 2
- 主要终点
- Feasibility and acceptability of the 12-week Tai Chi program
研究概览
简要总结
The main purpose of this randomized controlled trial was to assess the feasibility and acceptability of a 12-week Tai Chi program for community-dwelling older adults with chronic multisite pain and a history of falling. In addition, the investigators examined the effects of Tai Chi on pain characteristics, cognition, physical function, gait mobility, levels of pain-related biomarkers, fear of falling and rate of falls in these older adults.
详细描述
Older adults aged ≥65 years with multisite pain who reported falling in the past year or current use of an assistive device were recruited from Boston area communities. Participants were randomized to either a Tai Chi (N=28) or a light physical exercise (N=26) program, offered twice weekly for 12 weeks. The primary outcomes were feasibility and acceptability of the 12-week Tai Chi/light exercise program. Secondary outcomes included pain characteristics (pain severity and pain interference), cognition (attention and executive function), physical function (walking speed, strength, and balance), gait mobility (singe-task and dual-task gait), levels of pain-related markers (C-reactive protein, interleukin 6, tumor necrosis factor alpha, and beta endorphin), fear of falling, and rate of falls.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age of 65 years and older
- •Multisite (2 or more sites) musculoskeletal pain
- •At least one fall in the past year, or currently on an assistive device
- •A sedentary lifestyle
- •Be able to walk 20-feet without personal assistance
- •Be able to communicate in English.
排除标准
- •Regular Tai Chi practice
- •Unstable cardiac disease
- •Rheumatoid arthritis
- •Degenerative neuromuscular disease
- •Parkinson's disease
- •Terminal disease
- •Dementing illness
研究组 & 干预措施
Tai Chi
Individuals in the Tai Chi intervention group participated in a 12-week Tai Chi program.
干预措施: Tai Chi (Behavioral)
Light Exercise
Individuals in the exercise control group performed a 12-week light exercise program.
干预措施: Light Exercise (Behavioral)
结局指标
主要结局
Feasibility and acceptability of the 12-week Tai Chi program
时间窗: Over the 12-week intervention period
Feasibility and acceptability were evaluated by adherence, attendance, optimal program components, and safety.
次要结局
- Gait mobility(Before and after the 12-week intervention period)
- Fear of falling(Before and after the 12-week intervention period)
- Pain characteristics(Before and after the 12-week intervention period)
- Physical function(Before and after the 12-week intervention period)
- Rate of falls(Over the 12-week intervention and 6 months following the intervention)
- Cognition(Before and after the 12-week intervention period)
- Pain-related biomarkers(Before and after the 12-week intervention period)
研究者
Tongjian You
Associate Professor
University of Massachusetts, Boston