Characterization of the Microbiome in Cutaneous T Cell Lymphoma

Northwestern University2 个研究点分布在 1 个国家目标入组 300 人2019年1月30日

适应症Cutaneous T Cell Lymphoma

概览

阶段: 不适用
干预措施: Healthy controls
疾病 / 适应症: Cutaneous T Cell Lymphoma
发起方: Northwestern University
入组人数: 300
试验地点: 2
主要终点: Bacterial diversity index
状态: 招募中
最后更新: 昨天

概览研究者入排标准研究组 & 干预措施结局指标研究点相似试验

概览

简要总结

Investigators plan to perform a pilot study that aims to characterize the microbiome of human cutaneous T cell lymphoma patients and compare this to the microbiome of age and sex matched controls.

注册库

clinicaltrials.gov

开始日期

2019年1月30日

结束日期

2028年8月31日

最后更新

昨天

研究类型

Observational

性别

All

研究者

发起方

Northwestern University

责任方

Principal Investigator

主要研究者

Xiaolong (Alan) Zhou

Principal Investigator

Northwestern University

入排标准

入选标准

•Group 1: Patients with stage IA-IIA cutaneous T cell lymphoma
•Group 2: Patients with stage IIB and above cutaneous T cell lymphoma
•Group 3: Patients with CD30+ lymphoproliferative disorder including lymphomatoid papulosis and cutaneous anaplastic large cell lymphoma
•Group 4: Patients with plaque psoriasis with BSA\>5% on routine phototherapy per standard of care
•Group 5: Patients with moderate to severe atopic dermatitis on routine bleach bath therapy per standard of care
•Group 6: Healthy individuals without the above skin conditions, similar age and sex distribution to the patients with cutaneous T cell lymphoma
•All Groups: subjects who are age 18-89 years of age at time of enrollment
•All Groups: Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443).

排除标准

•All Groups: Subjects who are younger than 18 years of age or older than 90 years of age
•All Groups: Subjects who are unable to give consent
•Patients currently on systemic antibiotics or recent (within past 4 weeks) exposure to systemic antibiotics
•We will not recruit the following populations: adults unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant women, prisoners and other vulnerable populations.