NCT03095690已完成不适用
Determinants of Volumetric Bone Mineral Density at the Tibia and Radius and it's Relationship With Osteoporotic Fractures in Idiopathic Parkinson's Disease
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- Measurement of volumetric bone mineral density at the tibia and radius
研究概览
简要总结
Idiopathic Parkinson's disease (IPD) is the second most frequent neurodegenerative disease. Its association with osteroporosis and fragility fracture is now clearly demonstrated, but the determinants of this osteoporosis are yet to be explained. Our aim was to study factors associated with volumetric bone mineral density (vBMD) and bone microstructure at the tibia and radius in IPD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 35 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with idiopathic Parkinson's disease according to the criteria of the UKPDBB.
- •Parkinson's disease of moderate severity (Index HOEHN and Yahr <5)
- •Patient can respond to questionnaires, with or without help
排除标准
- •Patients with active psychiatric illness preventing the realization of examinations
- •Severe Parkinson's disease (Index HOEHN and Yahr ≥5 )
- •Heavy-morbidity including heart failure NYHA> 3 or chronic respiratory failure, terminal or severe renal impairment known dialyzed
- •Pregnancy
研究组 & 干预措施
Idiopathic Parkinson's Disease patients
Other
High resolution peripheral scanner (HRpQCT).
干预措施: High resolution peripheral scanner (HRpQCT). (Other)
结局指标
主要结局
Measurement of volumetric bone mineral density at the tibia and radius
时间窗: 0 hour
Measurement performed by High Resolution peripheral Quantitative Computed Tomography (HRpQCT)
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
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