Comparing Two Types of PRF Membranes in Management of Dehiscence Defect With Simultaneous Implant Placement in Posterior Mandible (Randomized Controlled Clinical Trial)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change in implant stability
研究概览
简要总结
Background: Placement of implants in an atrophic posterior ridge is a challenge for so many clinicians. The success of dental implants depends on the volume of alveolar bone available to provide stability. Bone grafting using xenograft with PRF and e-PRF as a membrane has shown promising results in both bone healing and defect reconstruction. Aim of the study: to evaluate the effect of Platelet-rich fibrin (PRF) and Extended Platelet-rich fibrin (e-PRF) as a membrane with xenograft to increase the width of ridge in posterior mandible with simultaneous implant placement.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with one or more missing posterior mandibular teeth.
- •Patient with atrophic posterior mandible with residual ridge width in the range of 4 to 6mm.
- •Patient with good oral hygiene and acceptable inter-arch space less than or equal to the restoration
排除标准
- •The patient underwent alveolar ridge reconstruction in the same area.
- •Patients with immune diseases, uncontrolled hypertension, and uncontrolled diabetes.
- •Patient with any pathological condition at the site of surgery.
- •Heavy smoker, alcohol abuse, parafunctional habits.
研究组 & 干预措施
PRF
干预措施: PRF membrane will be used with xenograft simultaneously with implant placement (Other)
e-PRF
干预措施: e-PRF membrane will be used with xenograft simultaneously with implant placement. (Other)
结局指标
主要结局
Change in implant stability
时间窗: baseline and 6 months
Osstell device will be used to measure the implant stability, primary stability Just after implant placement, and secondary stability 6 months from the time of implant placement. The measured values will be recorded in ISQ from 1 to 100, Implant stability is directly proportional to ISQ value
次要结局
- change in pain scores(uo to 7 days)
- Change in edema scores(up to 7 days)
- change in bone width gain(baseline and 6 months)
- change in bone density(baseline and 6 months)