The Risk for VTE Among Patients in the Medical Wards - Prospective Observational Study.
试验速览
- 阶段
- 不适用
- 入组人数
- 4,000
- 主要终点
- Thrombosis
研究概览
简要总结
Patients hospitalized in internal wards are at risk for VTE. The current guidelines recommend the use of thromboprophylaxis for 7-10 days among patients who are at increased risk for VTE. Yet several retrospective studies have shown that the compliance with this guideline is low. Physicians are often reluctant to administer LMWH to their fragile patients mainly because they are not convince that the risk associated with such therapy is greater than the risk for VTE.
In the current study, data concerning the use of thromboprophylaxis among patients admitted to the medical wards will be collected. The occurrence of bleeding or thrombotic event will be evaluated prospectively.
详细描述
Data concerning the use of LMWH among patients admitted to the medical wards at the Hadassah University Hospital will be collected prospectively from the electronic medical records. The occurrence of bleeding episodes or thrombotic events will be followed for the next 90 days following discharge from the hospital.
The percent of patients actually treated by LMWH among patients entitled for such therapy according to the most updated international guidelines will be evaluated. The risk of minor and major bleeding will be compared among those given thromboprophylaxis and those who were not treated. Similar comparison will be made for thrombotic events.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted to the medical wards at the Hadassah University Hospital
排除标准
- 未提供
结局指标
主要结局
Thrombosis
时间窗: 90 days
Rate of thrombotic events within 90 days following discharge
Compliance
时间窗: 90 days
Rate of compliance with ACCP guidelines concerning thromboprophylaxis of non-surgical patients.
Bleeding
时间窗: 90 days
Rate of minor and major bleeding episodes within 90 days following discharge
次要结局
未报告次要终点