Efficacy of a Physiotherapy, Speech and Language Therapy Intervention (PSALTI) for patients with chronic cough: a randomised controlled trial

King's College Hospital NHS Foundation Trust (UK)0 个研究点目标入组 88 人开始时间: 2011年7月29日最近更新: 2016年10月17日

试验速览

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•1. Patients with an isolated stable chronic cough >2 months in duration, normal chest X-ray and spirometry
•2. Persistent cough despite negative investigations and/or failed treatment trials for asthma, reflux and rhinitis
•3. Chronic cough >2 months
•4. Cough is the major respiratory symptom
•5. Sputum production absent or minimal (less than tablespoon/10ml a day)
•6. Patients with chronic asthma and Chronic Obstructive Pulmonary Disease (COPD) may be included in the study where their principle problem is cough (as felt by the patient)
•7. Male or female
•8. Upper Age Limit 100 years; Lower Age Limit 17 years

•1. Upper respiratory tract infection in past 4 weeks
•2. Taking angiotensin converting enzyme inhibitor medication
•3. Current smokers
•4. Patients with the following diagnoses of known respiratory disease will be excluded:
•4.1. Lung cancer
•4.2. Pneumonia
•4.3. Pulmonary fibrosis
•4.4. Sarcoidosis
•4.5. Pleural effusion
•4.6. Bronchiectasis and upper airway aspiration
•5. Patients with chronic/ acute asthma / COPD will be excluded from the study where their primary problem is not felt to be cough, ie primary problem may be breathlessness, excess sputum production or fatigue
•6. Patients with suspicious throat or layngeal mass, or with evidence of active aspiration (observed via Fibreoptic Endoscopic Evaluation of Swallowing (FEES) will be excluded

发起方

King's College Hospital NHS Foundation Trust (UK)