Diagnostic and Management of Hand Infection: a Retrospective Cohort in a Tertiary Care Center.
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 入组人数
- 1,400
- 试验地点
- 1
- 主要终点
- Percentage of treatment failure during the management of hand infections.
研究概览
简要总结
Primary or secondary (post-traumatic infections, notably related to bites, wounds, etc.) infections of the hand are very common situations, even if the epidemiology is poorly understood. For example, hand bite injuries represent 1.2 million referrals to the healthcare system per year in the United States. Their nosological framework extends from simple infections of the skin and soft tissues such as whitlows, to potentially severe deep damage such as arthritis and osteitis, or phlegmons of the tendon sheaths. The diagnostic approach is not consensual, and the contribution of additional biological parameters (inflammatory syndrome) and morphological investigations (x-rays, ultrasound, CT-scan or MRI) is not codified. Microbiology seems dominated by Staphylococcus aureus, but few studies have precisely described the microbial etiology. Consequently, probabilistic antibiotic therapy and the need to take bacteriological samples for secondary adaptation are not standardized. Likewise, surgical strategies (abstention, systematic washing or depending on evolution) remain operator dependent. We consequently aim to described diagnostic, management and related outcomes or hand infections in a specialized tertiary care center.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patient ≥ 18
- •yo followed-up for a hand infection in our tertiary care center
- •from 01/01/2014 to 31/12/2023, including
- •tendinous infections
- •septic arthritis
排除标准
- •osteomyelitis
结局指标
主要结局
Percentage of treatment failure during the management of hand infections.
时间窗: between 01/01/2014 and 31/12/2023.
Treatment failure will be defined as infection persistence or relapse, need of unplanned surgery for septic reason or infection-related death.
次要结局
未报告次要终点
