Comparison Amongst Scleral, Corneal and Amniotic Membrane Grafts to Restore Scleral Thinning
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 49
- 主要终点
- The surgical procedure was randomized in scleral, corneal or amniotic membrane graft. Nine patients underwent surgery with scleral graft that was covered by conjunctival flap; ten with corneal graft and ten with amniotic membrane transplantation.
研究概览
简要总结
The purpose of this study is to evaluate the use of preserved scleral, corneal and amniotic membrane graft for the surgical repair of scleral thinning of different sizes in patients underwent surgery of pterygium with associated beta therapy .
详细描述
Scleral thinning may occur secondary to different ocular surface conditions, especially in rheumatologic diseases and after surgeries as in pterygium. There are different methods to treat this condition, as to use scleral, corneal and more recently amniotic membrane graft.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with corneal scleral defects that have persisted for 1 years or longer, regardless of their cause. These patients will have received corneal-scleral or amniotic membrane transplant in order to correct scleral thinning
- •Patients with history of pterygium surgery associated with beta therapy followed by scleral thinning
排除标准
- •Ocular infection
- •Acute ocular inflammatory condition
- •Previous ocular surgery in the eye study
- •Non-controlled systemic disease such as rheumatoid arthritis
结局指标
主要结局
The surgical procedure was randomized in scleral, corneal or amniotic membrane graft. Nine patients underwent surgery with scleral graft that was covered by conjunctival flap; ten with corneal graft and ten with amniotic membrane transplantation.
时间窗: Patients were followed for 180 days.
次要结局
未报告次要终点