Evaluation of Platelet Rich Fibrin Use in the Treatment of Dry Socket.
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Influence of treatment on bacteria levels in wounds
研究概览
简要总结
The aim of the study is to evaluate the influence of PRF application in case of alveolar osteitis.
详细描述
The main objective was to compare the effects of using two different methods in the treatment of dry socket (alveolar osteitis), which is a postoperative complication of dental extraction. The first was Nipas, applied, if dry socket was diagnosed following a tooth extraction. In case of subsequent extraction of homonymous tooth and reoccurrence of dry socket, patients were treated with application of PRF.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •no known medical history of abnormal platelet counts,
- •patients with symmetric teeth qualified for extraction,
排除标准
- •patients treated previously for existing dry socket,
- •patients allergic to acetylsalicylic acid ,
- •systemic diseases,
- •pregnancy,
- •lactation,
- •drugs known to affect the number or function of platelets,
- •abnormal platelet counts,
研究组 & 干预措施
PRF application
Patients with alveolar osteitis in which PRF application was performed.
干预措施: PRF application (Procedure)
Aspirin application
Patients with alveolar osteitis in which Nipas was used.
干预措施: Nipas application (Drug)
结局指标
主要结局
Influence of treatment on bacteria levels in wounds
时间窗: 24 hours
The second part of the study was dedicated to analyzing the number of bacteria in tooth extraction wounds.
Intensity of pain vs. PRF and Nipas application
时间窗: 24 hours
In order to evaluate the relationship between intensity of pain after application of PRF and Nipas, Numeric Rating Scale pain scale is used. NRS is a horizontal line with an eleven point numeric range. It is labeled from zero to ten, with zero being an example of someone with no pain and ten being the worst pain possible. The higher score means worse outcome in case of present study.
次要结局
未报告次要终点