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临床试验/NCT03376542
NCT03376542已完成不适用

Cardiopulmonary Exercise Testing as an Outcome Predictor in Coronary Artery Bypass Surgery

Eduardo Tibirica, MD, PhD2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2017年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30
试验地点
2
主要终点
Mortality after cardiac surgery

研究概览

简要总结

This is a prospective cohort study of patients undergoing coronary artery bypass graft surgery. Prior to surgery, participants will undergo submaximal cardiopulmonary exercise testing on a treadmill. Participants will be followed for one month after surgery to assess mortality and non fatal complications.

详细描述

Coronary artery bypass surgery (CABG) is a complex and expensive procedure with great potential for morbidity and mortality. Preoperative evaluation is of paramount importance to optimize results. There is much evidence about the benefits of the cardiopulmonary exercise testing (CPET) in the evaluation of preoperative risk in non-cardiac surgeries. Thus, it is important to evaluate the relationship between parameters obtained in the CPET and the outcomes after cardiac surgery, especially CABG.

This is a prospective cohort study in which participants undergo submaximal CEPT on a treadmill prior to CABG. Participants will be followed up for one month after surgery to assess mortality and non fatal complications. It is expected that poor cardiopulmonary fitness is related to worse outcomes in CABG, as already observed in other cardiac pathologies and in non-cardiac surgery.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients undergoing coronary artery bypass grafting surgery at the National Institute of Cardiology, Ministry of Health, Rio de Jnaeiro, Brazil.

排除标准

  • Angina CCS IV, heart failure NYHA IV, inability to walk on a treadmill, severe left main coronary artery lesion.

研究组 & 干预措施

Cardiopulmonary exercise testing

Experimental

All patients included in the study will perform cardiopulmonary exercise testing prior to surgery

干预措施: Cardiopulmonary Exercise Testing (Diagnostic Test)

结局指标

主要结局

Mortality after cardiac surgery

时间窗: 30 days

number of deaths during the first 30 days after cardiac surgery

次要结局

未报告次要终点

研究者

发起方
Eduardo Tibirica, MD, PhD
申办方类型
Other Gov
责任方
Sponsor Investigator
主要研究者

Eduardo Tibirica, MD, PhD

Senior Researcher

National Institute of Cardiology, Laranjeiras, Brazil

研究点 (2)

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