Comparison of consumption of sevoflurane versus sevoflurane with dexmedetomidine using bispectral index and end tidal anaesthetic gas concentration in surgical patients under general anaeasthesia - a randomised controlled trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To determine the consumption of sevoflurane in comparison with sevoflurane and dexmedetomidine using Bispectral index and End tidal anaesthetic gas concentration.
研究概览
简要总结
This randomized controlled study compares the amount of sevoflurane used during general anaesthesia when given alone versus when combined with a single pre-induction dose of dexmedetomidine. Sixty adult surgical patients (ASA I–II) will be monitored using Bispectral Index (BIS) and End-Tidal Anaesthetic Gas concentration (ETAG) to maintain a uniform depth of anaesthesia. The study will measure total sevoflurane consumption, along with heart rate and blood pressure trends. The aim is to determine whether dexmedetomidine reduces sevoflurane requirement and provides better haemodynamic stability during surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anaesthesiologists Grade 1 and
- •Surgery under general anaesthesia.
- •Body mass index (BMI) lesser than 30 kg per square metre.
- •Patient willing to give informed consent.
排除标准
- •Patients allergic to study drug.
- •Alcohol abusers, history of psychiatric illness.
- •Altered mentation, epilepsy.
- •On beta blockers, sedative or stimulant drugs.
- •With uncontrolled hypertension and diabetes mellitus.
结局指标
主要结局
To determine the consumption of sevoflurane in comparison with sevoflurane and dexmedetomidine using Bispectral index and End tidal anaesthetic gas concentration.
时间窗: after intubation, every five minutes for half an hour, every fifteen minutes till extubation.
次要结局
未报告次要终点
研究者
Dr Taanya Mahesh
Sapthagiri Institute of Medical Sciences & Research Centre